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Prion diseases are also referred to as transmissible spongiform encephalopathies (TSE). They occur in humans and animals, primarily affecting the central nervous system.  They can be sporadic (spontaneous), familial (genetic/inherited) or acquired (transmitted by infection).  The hallmark of these diseases is the presence of microscopic vacuolization of the brain tissue, called spongiform degeneration (meaning that the tissue deteriorates, developing a spongy texture), and an abnormal protein, called scrapie prion protein (PrPSc), prion or abnormal prion protein.
Prion diseases are also referred to as transmissible spongiform encephalopathies (TSE). They occur in humans and animals, primarily affecting the central nervous system. They can be sporadic (spontaneous), familial (genetic/inherited) or acquired (transmitted by infection). The hallmark of these diseases is the presence of microscopic vacuolization of the brain tissue, called spongiform degeneration (meaning that the tissue deteriorates, developing a spongy texture), and an abnormal...
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